CORDIS Project
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This project focuses on improving tuberculosis (TB) control by investigating immune responses against both dominant and subdominant epitopes of the Mycobacterium tuberculosis bacterium. The goal is to develop a more effective vaccine strategy to prevent the reactivation of latent TB infections.
One third of the world's population is infected with latent TB, which therefore constitutes the largest reservoir for TB.
In 5% of latently infected individuals TB will eventually re-activate, and it is believed that most new TB cases is indeed due to re-activation of latent TB. TB is a chronic disease, and during the long interaction with the host, the immune response against TB antigens tend to focus on only a few dominant epitopes.
The idea for the project is that while a response against the…
STATENS SERUM INSTITUT
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