CORDIS Project
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The project focuses on developing tiny gold nanorods for enhanced photothermal imaging, enabling the detection of individual proteins in cellular environments. By utilizing near-infrared absorption, these nanoprobes aim to improve the study of neurotransmitter receptors and cell adhesion proteins.
Photothermal Imaging (PhI) is an absorption detection technique used for the detection of single gold nanoparticles (NPs), which can be a valuable tool to tackle complex cellular activities.
In order to study the dynamics of individual proteins in confined regions such as in neural synapses or in cell adhesion sites, small nanoprobes are needed.
Gold NPs (~ 5 nm) can be used, however their surface plasmon resonance (SPR) is centered at 530 nm, a spectral domain where absorption of cellular organ…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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