CORDIS Project
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This project aims to create advanced anticancer therapies using biocompatible titanium complexes that target tumors effectively while minimizing side effects. By linking active metal centers to bioactive components, the research seeks to develop innovative drug delivery systems for cancer treatment.
This proposal aims to develop custom designed anticancer therapeutic frameworks that are effective, stable, safe, and tumor targeted, based on the biocompatible TiIV metal.
The Tshuva group has established that water stable phenolato TiIV complexes are especially effective as anticancer agents both in vitro and in vivo, with markedly reduced side effects.
Optimal derivatives will be developed to combine activity, stability, and biological accessibility, by maintaining small steric bulk while inc…
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