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TheraSonic is a novel ultrasound-based system designed to isolate extracellular vesicles from small blood samples, aiming to improve early cancer detection and therapy. This platform enhances the purity and scalability of vesicle isolation, facilitating the discovery of specific cancer biomarkers and personalized treat…
This proposal develops a pioneering microscale ultrasound-based system to enrich extracellular vesicles (EVs) from µL volumes of whole blood and cancer spheroids, targeting early cancer detection and revolutionizing therapeutic approaches.EVs, nanoscale particles (30-1000 nm) released by mammalian cells, hold potential as biomarkers for cancer detection and as drug delivery vehicles due to their cell-specific cargo and ability to penetrate cell membranes.
However, current isolation methods like…
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
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