CORDIS Project
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This project explores RNA silencing, a critical gene regulation process in eukaryotes. It aims to understand the composition of RNA silencing complexes and their roles in cell differentiation and immune responses in plants and animals.
RNA silencing is a pan-eukaryotic gene regulation process that involves RNA molecules 19-30nt in length.
These molecules are produced by RNAse-III proteins in the Dicer family and engage into sequence-specific regulation of complementary DNA or RNA upon their incorporation into effector complexes. RNA silencing serves essential roles in biology but the molecular bases of its mechanisms are still poorly understood.
One major aspect of the proposed project is to decipher genetically the compositio…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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