CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project explores the role of epigenetics in cancer cell behavior, particularly how alternative splicing contributes to the epithelial-to-mesenchymal transition, which enhances tumor metastasis. It aims to identify regulatory mechanisms that could reverse this process.
Re-differentiation of carcinogenic epithelial cells to mesenchymal by epithelial-to-mesenchymal transition (EMT) confers properties to tumour cells, which turn them highly metastatic and resistant to chemotherapy.
Traditionally, it was thought that expression of key genes was enough to induce EMT.
However, very recently, alternative processing of transcribed genes into different matured mRNAs, and therefore proteins, by alternative splicing has also been implicated in EMT progression.
Even more,…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
