CORDIS Project
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This project explores the mechanisms behind tumor cell migration and its adaptability to different environments. By studying the role of endocytosis and the Endocytic Matrix, the research aims to identify how tumor cells switch migration modes, which is crucial for understanding cancer metastasis.
Tumor cells can adopt different modes of cell motility.
The ability to switch between diverse modes of migration enables tumors to adapt to micro-environmental conditions and to metastasize.
The critical pathways and cellular processes underlying the plasticity of tumor cell motility have only begun to be identified.Endocytosis, originally thought of as a device to internalize nutrients and membrane-bound molecules, is emerging as a connectivity infrastructure (which we call ""the Endocytic Matr…
IFOM-ISTITUTO FONDAZIONE DI ONCOLOGIA MOLECOLARE ETS
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