CORDIS Project
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This project investigates the role of specific proteins and lipids in establishing cell polarity, which is crucial for proper cell function and development. By studying these dynamics in yeast, the research aims to uncover mechanisms that could inform our understanding of diseases like cancer.
Cellular polarity is a universal feature of eukaryotic biology.
Failure to control cell orientation has dramatic consequences on embryogenesis and diseases including cancer.
The establishment of cellular polarity often entails the asymmetric distribution of plasma membrane (PM) lipids signaling proteins and vesicle trafficking.
The function of Rho proteins in cell polarity has been demonstrated from mammalian cells to yeast.
The small GTPase Cdc42 is a pivotal regulator of polarity establishment…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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