CORDIS Project
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This project investigates the mechanisms of nutrient-sensing neurons in the hypothalamus, focusing on their role in obesity and insulin resistance. By employing advanced techniques in cell physiology and molecular imaging, the research aims to uncover how these neurons contribute to metabolic health and disease.
Type 2 diabetes is one of the most common chronic diseases in the world, and the number of those affected has been raising dramatically in recent years.
In type 2 diabetes the body fails to use insulin effectively, which leads to the chronic increase in blood glucose that characterises the disease.
It is not known why the body becomes resistant to insulin but evidence suggests that an imbalance between energy intake, storage, and expenditure can lead to obesity and insulin resistance.
Thus, to u…
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