CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project examines the role of Ectodermin in colorectal cancer, focusing on its function as an inhibitor of tumor-suppressive signals. The research aims to explore genetic modifications that could enhance responsiveness to these signals and limit tumor progression.
Colorectal cancer (CRC) is a leading cause of cancer-related death in western countries. TGFb are a family of signaling molecules delivering crucial tumor-suppressive signals to different cell types.
Lack of TGFb induced cytostasis is a hallmark of cancer, and mutations of key transducers of TGFb in Colorectal cancer (CRC), albeit found only in a subset of tumors, indicates a leading role for these signals in limiting tumor progression.
In our lab we identified Ectodermin, a molecule that antago…
UNIVERSITA DEGLI STUDI DI PADOVA
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
