CORDIS Project
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The project aims to explore the mechanics of touch sensation by studying how sensory neurons detect mechanical forces. It focuses on the role of specific ion channels and their interactions with the extracellular matrix, aiming to develop technologies to manipulate these components for better understanding and potentia…
Touch sensation is built upon the ability of sensory neurons to detect and transduce nanometer scale mechanical displacements.
The underlying process has been termed mechanotransduction: the high sensitivity and speed of which is enabled by direct gating (opening) of ion channels by mechanical force.
Force detection is functionally compartmentalized and only takes place at the peripheral endings of sensory neurons in vivo.
Two molecules are known to be genetically necessary for touch in many sen…
MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
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