CORDIS Project
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This project explores the role of microRNAs in T cell communication and regulation, particularly their transfer between different T cell populations. It aims to understand how these interactions influence T cell development and immune responses.
MicroRNAs (miRNAs) can be transferred between cells, representing an exciting new dimension to intercellular communication, referred to as non-cell-autonomous gene regulation.
We recently identified that distinct miRNAs are packaged and exported from TREG cells and delivered directly to TH1 cells, suppressing T cell-mediated disease.
Different T cell populations express different miRNAs and release a distinctive set of extracellular miRNAs.
In this proposal we will identify whether the transfer…
THE FRANCIS CRICK INSTITUTE LIMITED
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