CORDIS Project
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This project investigates the immune responses of fish B cells, focusing on their role in mucosal immunity. It aims to understand how these cells function in the absence of organized follicles and their implications for vaccination.
B cells are one of the main players of immunity, responsible for the production of immunoglobulins (Igs).
In 2011, I was granted an ERC Starting grant to undertake the phenotypical and functional characterization of teleost B lymphocytes based on the hypothesis that they do not behave as mammalian B2 cells (conventional B cells) but closely resemble mammalian innate B1 lymphocytes involved in extrafollicular T-independent (TI) responses.
Since then, my laboratory has gathered considerable eviden…
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