CORDIS Project
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This project investigates the role of mobile genetic elements, or transposable elements, in embryo formation and organ development. By utilizing advanced genome engineering and sequencing techniques, it aims to uncover how these elements influence both normal and pathological embryonic processes.
The formation of a functional embryo is dictated by precise genetic and morphogenetic events.
Yet, focusing solely on gene expression does not seem sufficient to explain all developmental phenotypes.
Mobile genetic elements (or transposable elements, TEs) have been little studied in the context of cellular differentiation and organogenesis. I propose that TEs contribute to embryo formation, both in physiological and pathological contexts.
Nearly all eukaryotic genomes contain TEs, which account…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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