CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the Wnt signaling pathway's role in regulating the TCF4 transcription factor during the development of intestinal stem cells into differentiated cells. By employing advanced techniques, it aims to identify regulatory elements and protein complexes involved in this process, which is crucial for…
The Wnt pathway is a key regulatory pathway in development and carcinogenesis.
Many of the components of the pathway connecting Wnt to the transcription factor TCF4 have been identified.
However, our knowledge of the regulation of TCF4 promoter and enhancer elements in response to the Wnt signal, resulting in development from a stem cell to a differentiated cell, is limited.
Largely due to technical constrains it has not been possible to identify TCF4 bound DNA enhancer elements or protein compl…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
