CORDIS Project
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The TBNANO project aims to enhance tuberculosis treatment by developing nanocapsules that deliver antitubercular drugs directly to infected macrophages. By using biocompatible materials and targeting ligands, this approach seeks to improve drug uptake and reduce side effects, potentially revolutionizing the management…
Tuberculosis (TB) is still a major public health problem worldwide.
It is estimated that more than one-quarter of the world's population is infected with this airborne infectious disease.
Moreover, the increase of multidrug- and extensively drug-resistant TB is alarming. TB is caused by Mycobacterium tuberculosis, an intracellular pathogen that can survive in host cells, mainly in macrophages.
The uptake of the antitubercular drugs by infected host cells is limited.
The orally or intravenously a…
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