CORDIS Project
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This project aims to create the largest collection of DNA samples from tuberculosis patients and healthy controls to identify human genetic factors that influence susceptibility to TB. It will also analyze the genetic characteristics of TB strains and their interactions with the host immune response.
We propose to extend an existing collection of DNA extracts from TB patients and their corresponding TB DNA to establish the world’s largest resource of extracts from a population of TB patients and 5000 ethnically matched healthly controls.
The bank will comprise 5000 DNA host DNA extracts paired the DNA and cultures of the strain of Mycobacterium tuberculosis causing their disease.
We will perform a genome-wide scan to discover human genes predisposing to TB.
We will then localise causal va…
QUEEN MARY UNIVERSITY OF LONDON
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THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom, Cambridge
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
KLINIKUM DER UNIVERSITAET ZU KOELN
Germany, Koeln
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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