CORDIS Project
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The project focuses on developing advanced ultrasound imaging techniques using targeted microbubbles to detect and treat bacterial infections associated with cardiac devices. By enhancing the specificity and sensitivity of ultrasound diagnostics, it aims to improve patient outcomes in cardiology and microbiology.
Due to an aging population, increasingly more cardiac devices are implanted (pacemaker/ICD/CRT/ prosthetic valve/LVAD; worldwide ~2 million yearly).
Life-threatening bacterial infections (1-60% infection and 29-50% mortality rate) associated with these devices are a major healthcare burden and pose scientific challenges.
Ultrasound imaging is currently the primary diagnostic modality.
However, it lacks specificity and sensitivity because the signal from the bacteria is similar to the signal of h…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
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