CORDIS Project
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The TargetCTC project aims to improve cancer treatment by developing nanoarchitectures that target circulating tumor cells (CTCs) using a novel strategy that utilizes neutrophils. These nanoarchitectures are designed to deliver drugs directly to tumors, enhancing therapeutic efficacy and potentially reducing cancer spr…
Metastasis is the leading cause of cancer-related deaths, primarily driven circulating tumor cells (CTCs) that migrate from the primary tumor site and colonize distant organs.
Conventional therapies are often ineffective in efficiently targeting these CTCs, leading to cancer progression and recurrence.
The TargetCTC proposes the development of anti-EpCAM nanobody-functionalized dendritic polyglycerol sulfate (dPGS)-based nanoarchitectures designed to specifically target CTCs using a novel ""hitc…
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