CORDIS Project
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This project investigates tanycytes, glial cells in the hypothalamus, and their primary cilia, termed tanycilia. It aims to understand how these structures sense nutrients and hormones to regulate metabolism, particularly in the context of obesity and anorexia, using advanced genetic and imaging techniques.
Obesity and metabolic diseases are a top priority challenge for health systems.
Monitoring changes in the bodys energy levels is a task of the hypothalamus (HpT) which integrates the actions of peripheral hormones and nutrients with neural information.
However, this regulation is complex, and the causes and biological mechanisms leading to metabolic disorders remain to be explored.
Among the cells involved, tanycytes play a key role.
They are glial cells that line the third ventricle and mediate…
UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN
UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN
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