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The MECHANOCONTROL project investigates how mechanical forces influence cell behavior and tumor development, particularly in breast cancer. It focuses on inhibiting the interaction between specific cytoskeletal proteins to develop new therapeutic drugs for pancreatic cancer, addressing a significant clinical need.
Mechanical forces transmitted between cells and their microenvironment drive cell function and regulate tumorigenesis.
Due to this importance, our FET PROACTIVE project MECHANOCONTROL aims to understand the molecular mechanisms by which forces exert their role, and their implications in the specific application of breast cancer.
In this context, we have recently identified that the interaction between the cytoskeletal molecules vinculin and talin can be inhibited by a vinculin fragment (VD1) whi…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
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