CORDIS Project
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This project explores the role of solute carrier transporters in dendritic cells, focusing on their involvement in immune responses and metabolism. By studying these transporters, the research aims to enhance understanding of immune function and potential therapeutic targets.
Phagocytes are confronted daily with the dreaded task to respond to billions of dying cells and a plethora of external pathogens.
Dendritic cells (DCs) comprise a heterogeneous group of phagocytes that are equipped with several phagocytic and pathogen recognition receptors (PRRs), and with the processing machinery to mediate efficient elimination of apoptotic or infectious cargos.
This, in turn, helps to maintain tissue homeostasis and prevent autoimmunity.
However, there is fast-growing evidenc…
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