CORDIS Project
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This project investigates the Type VI Secretion system in bacteria, focusing on how proteins are transported across cell membranes. By creating a detailed model of this process, the research aims to enhance understanding of bacterial interactions at molecular, cellular, and intercellular levels.
Transporting selected proteins across the cell envelope in a controlled manner is a fundamental property of all cell types.
For bacteria, secretion systems play a central role in the translocation of effectors that mediate interactions with other cells.
The bacterial Type VI Secretion (T6S) system is one of the most widespread secretion systems and, in a cell-cell contact-dependent fashion, it injects effectors into eukaryotic and bacterial targets.
The T6S system utilizes a cytoplasmic phage ta…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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