CORDIS Project
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The T-REaCT project aims to map the interactions between T cells and somatic mutations during cancer evolution. By utilizing single-cell genomics, it seeks to improve early cancer detection and develop personalized immunotherapies.
Cancers are characterized by the accumulation of somatic mutations in the DNA.
The human immune system can detect such mutations in cancers via T cells, which forms an important factor in the activity of clinically used cancer immunotherapies.
What challenges our classic view of cancer formation are the recent breakthrough discoveries showing that somatic mutations are ubiquitously found in healthy tissues - why only some of these mutations lead to clonal outgrowths and what are the factors sust…
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
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United States, NEW YORK
Type: Research institute
Activity type: Research Organisations
SME: No
Joan & Sanford I Weill Medical College of Cornell University
United States, New York
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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