CORDIS Project
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This project focuses on advancing mass spectrometry techniques to study protein interactions and diversity in their natural cellular environments. By developing methods for high-throughput screening and whole-organ analysis, it aims to enhance our understanding of protein structures and their biological roles across va…
Protein structure and consequently function is influenced by the cellular content.
The array of splice variants, post-translational modifications, cleavages and the ability to bind cofactors and drugs, is governed by the surrounding cellular milieu.
This is determined by internal and external cues such as cell type, developmental stage, stress conditions, disease and aging, which give rise to an ensemble of distinct protein entities.
To study this diversity, there is a need for methods that enab…
WEIZMANN INSTITUTE OF SCIENCE
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