CORDIS Project
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This project focuses on developing innovative oncolytic herpesviruses that specifically target HER2-positive tumors. The goal is to enhance the systemic delivery of these viruses for treating metastatic cancers, addressing significant clinical needs and improving therapeutic options for patients.
Solid tumors, in particular metastatic ones, represent unmet clinical needs and the second cause of death worldwide.
Oncolytic viruses (OVs) kill tumors and spare normal cells.
They are a distinct class of novel anti-cancer agents, frequently administered by intratumoral injection. A Holy Grail in the innovation of OVs is the possibility to administer them by systemic, e.g. intravenous injection, so that in the human body OVs search for metastases and scavenge them.
The systemic delivery of OVs…
Fondazione Policlinico Sant'Orsola
FONDAZIONE POLICLINICO SANT'ORSOLA ONLUS
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Italy, Bologna
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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