CORDIS Project
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This project investigates the oscillation of the NfκB pathway in inflammatory bowel disease (IBD) using animal models and patient samples. By developing a validated model, it aims to identify critical components affecting inflammation and explore potential therapeutic interventions.
Inflammatory bowel disease (IBD) is a major health problem with severe co-morbidities, requiring life-long treatment.
Oscillating processes, like biological clocks are well studied and modeled in a number of systems.
Circadian rhythms are extremely important for optimal treatments of patients.
Recently, the NfkB pathway has been shown to be oscillating.
In this project, we will model NfkB oscillation in chronic inflammatory bowel diseases in animal models and patient cohorts with immunosuppressi…
THE UNIVERSITY OF MANCHESTER
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Germany, Kiel
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Heidelberg
Type: Research institute
Activity type: Research Organisations
SME: No
United Kingdom, COVENTRY
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Aachen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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