CORDIS Project
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This project studies how the genome and proteome influence cell growth, shape, and polarity using the fission yeast model. It combines microscopy, gene knockouts, and computational methods to provide insights into cellular processes and their implications for disease.
A major challenge of modern biology is to elucidate how cellular structure and function result from the systemic action of the genome and proteome.
In this proposal, we describe an integrated approach combining high-content and quantitative microscopy, systematic gene knockouts, and computational/theoretical methods to carry out the most detailed systemic study of three key aspects of cell physiology: growth, shape and polarity.
We will use the fission yeast Schizosaccharomyces pombe as experime…
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