CORDIS Project
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This project investigates the molecular mechanisms of synapse formation and function, focusing on synaptic organizer proteins. By understanding these processes, the project aims to develop strategies for repairing synapses and restoring cognitive functions in models of Alzheimer's disease.
Synapses are the specialized cellular junctions that form the basic units of communication between neuronal cells.
Given the variety of network-dependent functions that synapses need to support, a fundamental question is how their properties are specified at the molecular level.
Membrane-anchored and soluble “synaptic organizer proteins” form adhesive interactions that mediate synapse formation and differentiation.
However, a structural and mechanistic understanding of how they recruit and organ…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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