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The SYNKIT project focuses on improving natural killer cell immunotherapy for cancer treatment by genetically engineering cells derived from induced pluripotent stem cells. The goal is to enhance their persistence and functionality in combating tumors.
Cancer remains a leading cause of death worldwide, urging for innovative therapies.
Infusion of natural killer (NK) cells, which possess an intrinsic capacity to eliminate cancer cells, is a promising treatment option for various tumours.
Genetic engineering of NK cells before transfer allows to specifically tailor and modulate their anti-tumour responses.
One particularly attractive strategy for broad implementation of NK cell immunotherapy in an “off-the-shelf” setting is to expand large numbe…
KAROLINSKA INSTITUTET
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