CORDIS Project
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This project investigates how neuronal activity influences synapse specificity in the olivocerebellar network, which is crucial for motor control and cognitive processes. By developing new genetic tools, the research aims to uncover the molecular basis of synapse identity and its regulation.
The mature brain results from the formation of precise networks between functionally and morphologically distinct types of neurons. A given neuron forms synapses with a limited number of partners and on precise subcellular localizations.
Understanding what controls this specificity is mandatory not only to understand brain functions but also the aetiology of synaptopathies such as autism spectrum disorders or schizophrenia.
Various molecules define the identity of each type of synapse.
Furthermo…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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