CORDIS Project
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This project focuses on the communication between the gut and the brain, particularly through enterochromaffin cells that release serotonin. It aims to understand the mechanisms of hormone secretion and how these cells may form synapse-like connections to regulate gut-brain signaling.
Communication between the gastro-intestinal (GI) tract, the enteric nervous system (ENS), and the brain plays an important role in regulating our behaviour, and accordingly, impairments in this communication have been implicated in the pathogenesis of multiple disorders including obesity, diabetes, visceral pain, and inflammatory bowel diseases. A better understanding of the molecular and cellular mechanisms of gut-to-brain signalling will be critical for treating these disorders.
An important g…
KOBENHAVNS UNIVERSITET
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