CORDIS Project
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This project investigates the dynamic interactions between the endoplasmic reticulum and mitochondria in neurons, focusing on how these interactions influence synaptic plasticity and neuronal function. Using advanced super-resolution microscopy, it aims to reveal the role of inter-organelle communication in maintaining…
The endoplasmic reticulum (ER) can rapidly reorganize its functional domains and inter-organelle communication sites in response to cellular demands. ER-mitochondria communication is essential for normal cell physiology, as it conveys lipid exchange, mitochondrial calcium uptake, among other vital processes for mitochondrial function.
In neurons, activity-mediated dynamics of ER and mitochondria are required for synaptic responsiveness to induction of synaptic plasticity and stimulating neuronal…
KUNGLIGA TEKNISKA HOEGSKOLAN
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