CORDIS Project
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This project focuses on developing a microfluidic platform for high-throughput screening of drug combinations in 3D cell cultures. By enhancing the efficiency of drug discovery, it aims to identify synergistic effects that can improve treatment outcomes for various diseases.
Drug combinations can lead to the discovery of novel drugs by increasing efficacy or lowering toxicity through synergy.
This can boost existing drugs, rescue drug candidates, and accelerate drug discovery for yet poorly addressed diseases.
However, predicting synergy is difficult, and finding synergies requires high-throughput screening (HTS) in advanced cell models.
Current solutions propose either HTS in 2D cell cultures or low throughput assays in 3D cell cultures, but not both.On the basis o…
ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS
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