CORDIS Project
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This project investigates how neurons maintain energy levels for synaptic transmission, focusing on the mechanisms that regulate ATP production through glycolysis and oxidative phosphorylation. By employing advanced imaging techniques, the research aims to uncover the molecular processes that ensure metabolic integrity…
Synaptic transmission is an extremely energetically-demanding process that consumes 75% of the energy required for brain function.
However, it remains poorly understood how synapses guarantee the necessary ATP levels required for neurotransmission.
While our understanding of the metabolic pathways for ATP production is vastly detailed, very little is known about the actual molecular implementation of these pathways in neurons for sustaining synaptic bioenergetics. I hypothesize that tightly-regu…
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE
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