CORDIS Project
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This project investigates synaptic adhesion molecules that determine the connectivity of neurons in the brain. By understanding how these molecules function, the research aims to shed light on cognitive disorders and develop new treatment strategies.
Synapses connect neurons into a network that encodes our thoughts, memories and personalities.
Loss of synaptic connectivity is thought to underlie a variety of cognitive disorders such as autism, schizophrenia and Alzheimer’s disease, but little is known about the molecules and mechanisms that establish and maintain the precise patterns of synaptic connectivity in the brain.
Neither is it understood how perturbed synaptic connectivity affects cognitive function.
The synaptic adhesion molecules…
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