CORDIS Project
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This project aims to develop advanced methods for producing complex carbohydrate structures on cell surface proteins. By creating diverse libraries of glycans, the research will enhance understanding of glycan binding proteins and their roles in various physiological and disease processes, particularly in immunology an…
Almost all cell surface proteins are modified by covalently-linked carbohydrates and the glycan structures on these glycoproteins are mediators of many physiological and disease processes.
Despite their importance, there are no methods available to systematically and efficiently produce libraries of complex glycans to investigate specificities and biology of glycan binding proteins.
To address this deficiency, we will develop chemoenzymatic technologies that can provide large collections of glyc…
UNIVERSITEIT UTRECHT
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