CORDIS Project
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This project aims to develop a novel cancer therapy using xeno-autoantibodies derived from a dietary carbohydrate antigen. By leveraging interdisciplinary approaches, it seeks to enhance the targeting of cancer cells and improve diagnostic and therapeutic outcomes.
Immunotherapy recently became an important alternative to conventional treatment regimes, yet cancer remains a universal leading cause of death.
Thus, novel cancer theranostic approaches are still much desired.
Although altered cell surface glycosylation is one of the hallmarks of cancer, targeting this ‘sweet aim’ for cancer therapy has been elusive, largely due to carbohydrates poor immunogenicity and the low affinity of antibodies against them. A red meat-derived carbohydrate antigen is a nov…
TEL AVIV UNIVERSITY
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