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The SupraValent project focuses on developing advanced biomaterials that replicate the dynamic behavior of natural extracellular matrices. By combining supramolecular and covalent bonds, the project aims to create tough hydrogels with controlled properties for various applications.
Current biomaterials poorly recapitulate the tough, responsive, and spatiotemporal behavior of native extracellular matrices (ECM).
This recapitulation of ECM complexity is imperative to create environments that can effectively communicate with living cells. A key missing component in synthetic ECM-mimetics is spatiotemporal control of material dynamics.
Supramolecular biomaterials hold significant promise to fill this need, yet their poor mechanical properties often limit application. I hypothe…
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