CORDIS Project
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This project focuses on creating hybrid materials that mimic the complex mechanical properties of the extracellular matrix to guide the differentiation of induced pluripotent stem cells into cardiomyocytes. By controlling the mechanical environment, the project aims to enhance stem cell research and tissue engineering…
The biochemical and biophysical cues of the stem cell environment that act in a concerted and spatiotemporal manner lead to the formation of the 200 cell types and organs of the human body, but how this precisely occurs remains unclear and it is necessary to guide their production for use in the biomedical area.
Standard differentiation protocols in vitro mimic known stages in development by the timed addition of biochemical cues on 2D substrates, however these protocols lack the complexity of t…
UNIVERSITEIT LEIDEN
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