CORDIS Project
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This project focuses on enhancing the efficiency of baker's yeast, Saccharomyces cerevisiae, used in various industries by addressing the Crabtree effect, which limits biomass production. By identifying and utilizing specific natural alleles, the project aims to develop superior yeast strains for improved fermentation…
The common baker's yeast, Saccharomyces cerevisiae, is used in various industrial applications, ranging from the production of fermented beverages like beer and wine, foods including bread and chocolate, bioethanol, enzymes and pharmaceuticals. S. cerevisiae cells can grow aerobically, using the TCA cycle and electron transport chain to produce around 16 to 18 molecules of ATP (energy) per glucose molecule.
However, when glucose concentrations exceed about 1% (w/w), the cells tend to shut down t…
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