CORDIS Project
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This project explores enhancing the safety and efficacy of live viral vaccines by incorporating small-hairpin RNAs to inhibit wild-type virus replication and boost immune response. It aims to improve vaccine design for better disease control.
Live vaccines represent one of the most important and effective interventions against the spread of viral disease.
As such, they are instrumental in addressing ongoing societal challenges in areas such as healthcare and global food security.
However, their capacity to genetically recombine with wild type (WT) viruses circulating in the field remains a primary safety concern.
Modifying live vaccine strains to reduce such occurrences would be highly desirable from a safety perspective.
Also effort…
UNIVERSITE DE LIEGE
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