CORDIS Project
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This project explores the role of SUMOylation, a protein modification, in regulating synaptic transmission and its implications for neurological diseases. It aims to identify SUMOylated proteins, understand their functions, and investigate their protective effects against excitotoxicity in neurons.
Synaptic protein SUMOylation is a completely new and exciting field of investigation.
This application will investigate the roles of SUMOylation in normal and pathological synaptic transmission.
The functional and pathophysiological implications for synaptic protein SUMOylation are far-reaching. SUMOylation has already been implicated in a diverse array of synaptopathies.
Therefore, better understanding of the regulation and consequences of synaptic SUMOylation is of fundamental importance.
The…
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