CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of cysteine oxidation in cellular signaling, focusing on the formation of sulfenic acids. By studying Escherichia coli, it aims to identify how these modifications influence protein function and cellular processes, potentially revealing new regulatory mechanisms.
Within proteins, cysteine residues are sensitive to oxidation by reactive oxygen species (ROS).
The first oxidation product of cysteines exposed to ROS is the sulfenic acid derivative (-SOH).
Sulfenic acids are highly reactive intermediates that, unless they are stabilized within the protein microenvironment, react with another cysteine present in the vicinity to form a disulfide or are further oxidized to the irreversible sulfinic (-SO2H) and sulfonic (-SO3H) acid modifications.
Sulfenic acid f…
UNIVERSITE CATHOLIQUE DE LOUVAIN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
