CORDIS Project
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This project aims to develop a new malaria vaccine by characterizing unique glycosylations on the Plasmodium falciparum parasite. By understanding these surface features, the research seeks to create a vaccine that provides long-lasting protection against malaria.
Annually, malaria causes 200 million clinical cases and more than half a million deaths.
Works carried out more than 40 years ago demonstrated that a malaria vaccine offering sterile protective immunity in humans was possible, but the efforts to develop a modern, recombinant ‘subunit’ malaria vaccine only confer short term protection against clinical malaria in 35-50% of recipients.
Several evidences support the presence of foreign short N-glycans and other minor glycosylations in the surfaces o…
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
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