CORDIS Project
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This project aims to identify the specific receptors used by human influenza A viruses to enhance vaccine development. By understanding glycan specificity and creating better laboratory models, it seeks to improve vaccine efficacy and surveillance techniques.
Our current assays to determine the receptor specificity and vaccine efficiency of influenza A virus fail as they do not represent receptors available in the human upper respiratory tract.
The lack of these receptors in our laboratory hosts to create vaccines significantly dampen yields, the resulting mismatched vaccines do not afford proper protection and further drive antigenic drift.
The objective of this proposal is to elucidate the functional receptor of human influenza A viruses.
By using…
UNIVERSITEIT UTRECHT
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