CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
SUCCESSion aims to understand how the order of genetic mutations affects the transformation of normal cells into cancerous ones. By developing new gene editing technologies, the project will study how mutations interact with the cellular environment to influence tumor initiation.
Mutant cells are abundant in normal tissues, but only very few will transform into life-threatening cancer.
The triggers for these mutant clones to transform are unclear.
Phylogenetic studies of solid cancers hinted towards an impact of the order of mutation acquisition on the malignant potential of mutant clones.
However, to date, no functional studies exist validating these findings in the in vivo context.Mutant clones closely interact with their environment.
Intravital microscopy experiments…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
