CORDIS Project
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This project focuses on developing innovative gene editing technologies by studying unique viruses that utilize protein-primed DNA replication. The aim is to create a new method for amplifying and delivering DNA into cells, enhancing the potential for treating genetic diseases.
There are over 6,000 human genetic diseases, affecting hundreds of millions of people.
The vast majority are caused by small mutations in DNA sequences which are potentially correctable, so the development of new gene editing tools will have major benefits for treating human genetic diseases.
To tackle this challenge, we will harness the natural protein diversity of viruses to create new gene editing technologies.We will study an unusual class of viruses that use a unique mechanism to replicate…
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