CORDIS Project
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This project investigates the interplay between type 2 diabetes and late onset Alzheimer's disease by studying the effects of diabetes on biochemical and behavioral features in genetically modified mice. It aims to uncover how genetic and environmental factors contribute to the disease.
Different from the familial forms, late onset Alzheimer’s disease (LOAD) is not the consequence of a single cause: neither aging, nor genetic polymorphisms nor an environmental disturbance do, per se, suffice to produce this disease.
It is currently thought that instead disease is the consequence of an interaction of all the above circumstances.
With that perception in mind, I here propose to study i) the effect of type 2 diabetes mellitus (T2DM), a metabolic disturbance strongly associated with…
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