CORDIS Project
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This project investigates the diverse roles of different subsets of dendritic cells in the skin, focusing on their functions in immune regulation. By studying these subsets, the research aims to enhance understanding of immune responses to pathogens and the maintenance of tolerance to harmless antigens.
The skin is a fascinating tissue at the level of immune regulation.
As barrier with the outside world, it is in constant contact with innocuous environmental antigens, but it is also the entrance site for pathogens.
Dendritic cells (DCs) play an essential role in initiation and regulation of immune responses.
Thus, skin DCs appear to mediate two seemingly incompatible functions: maintaining tolerance against harmless self and environmental antigens constantly present in the skin, while retaining…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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